Status:

COMPLETED

Use of Clorhexidine Dressings to Reduce Surgical Site Infections in Breast Cancer Surgery. A Controlled Clinical Trial

Lead Sponsor:

National Institute of Cancerología

Collaborating Sponsors:

Instituto Nacional de Rehabilitacion

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

Surgical site infection (SSI) after breast and axillary surgery occurs more often than for other clean surgical procedures. Infection in the setting of sick woman could delay the adjuvant therapy and ...

Detailed Description

Following approval by the National Cancer Institute Review Board, eligible subjects will be recruited prospectively from the Breast Cancer Department at National Cancer Institute, México from November...

Eligibility Criteria

Inclusion

  • Females minimum age 18 able to give informed consent
  • Breast cancer confirmed by histopathology
  • Patients undergoing unilateral or bilateral mastectomy with or without immediate expander reconstruction.

Exclusion

  • Males
  • Patients who deny informed consent
  • Prior radiation therapy to the sick breast.
  • Pregnant or breastfeeding women
  • Patients undergoing immediate breast reconstruction with Deep Inferior
  • Epigastric Perforator (DIEP) o Transverse Rectus Abdominal Muscle techniques (TRAM) .
  • Emergency procedures
  • Documented allergy to chlorhexidine gluconate
  • Antibiotic use in the fourteen days prior to surgical date
  • Patients with a history or suspicion of breast cancer surgery outside the INCan in the previous three months.
  • Patients who do not speak spanish, diagnosed with a psychiatric disorder and in whom a minimum follow-up of 14 days couldn't be feasible because of operative difficulties (eg.
  • place of residence or reference to other health institutions).

Key Trial Info

Start Date :

October 3 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 30 2018

Estimated Enrollment :

116 Patients enrolled

Trial Details

Trial ID

NCT03229824

Start Date

October 3 2016

End Date

May 30 2018

Last Update

November 13 2018

Active Locations (1)

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1

Instituto Nacional de Cancerología

Mexico City, Mexico City, Mexico, 14080