Status:
COMPLETED
Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
University of South Alabama
Conditions:
Ventilator-Induced Lung Injury
Respiratory Distress Syndrome
Eligibility:
All Genders
1-3 years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to determine, in preterm infants less than 37 weeks gestation with respiratory distress who are ventilated in the first 48 hours after birth, if mid frequency ventilation ...
Detailed Description
In preterm infants with respiratory distress syndrome (RDS) who are ventilated in the first 48 hours after birth, mid frequency ventilation (MFV) strategy, compared with standard frequency ventilation...
Eligibility Criteria
Inclusion
- Infants ≥ 23+0/7 weeks and ≤ 36+6/7 who are intubated and mechanically ventilated for respiratory distress syndrome (defined by use of surfactant) within 48 hours after birth
- Infants whose parents/legal guardians have provided consent for enrollment
- Inborn or outborn infants transferred to this center before 48 hours after birth
- Ventilator rate ≤ 80 per minute prior to enrollment
Exclusion
- a major malformation, a neuromuscular condition that affects respiration, or terminal illness or decision to withhold or limit support.
Key Trial Info
Start Date :
August 2 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 10 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03231735
Start Date
August 2 2017
End Date
October 10 2024
Last Update
October 15 2024
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35249
2
University of South Alabama
Mobile, Alabama, United States, 36604