Status:
COMPLETED
Clearance of Inflammatory Cytokines During Renal Replacement Therapy Using the EMIC®2 Filter
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Conditions:
Acute Renal Failure
Eligibility:
All Genders
18+ years
Brief Summary
This study will be conducted in patients with sepsis and acute kidney injury needing renal replacement therapy. The aim is to investigate whether continuous renal replacement therapy with the EMIC®2 ...
Detailed Description
In patients with acute kidney injury (AKI) and sepsis requiring renal replacement therapy, the investigators aim to determine whether continuous veno-venous haemodialysis with an EMiC®2 filter leads t...
Eligibility Criteria
Inclusion
- adult patients (≥18 years) in the Critical Care Unit with AKI and sepsis
- clinical decision that citrate based continuous veno-venous haemodialysis (CVVHD) is necessary
Exclusion
- lack of consent
- pre-existing dialysis dependent renal failure
- life expectancy \<24 hours
- patients with haemoglobin \<7g/dL (unless transfused for clinical reasons)
- need for extracorporeal membrane oxygenation (ECMO)
Key Trial Info
Start Date :
July 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2018
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT03231748
Start Date
July 1 2017
End Date
July 1 2018
Last Update
October 23 2019
Active Locations (1)
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1
Guy's & St Thomas Hospital
London, United Kingdom, SE1 7EH