Status:

COMPLETED

Effect of Ramosetron on Heart Rate-corrected QT Interval During Robot-assisted Laparoscopic Prostatectomy With Steep Trendelenburg Position

Lead Sponsor:

Yonsei University

Conditions:

Prostate Cancer

Eligibility:

All Genders

20-80 years

Phase:

NA

Brief Summary

Intraperitoneal insufflation of carbon dioxide may affect the sympathetic activity that leads to changes in ventricular re-polarization. This in turn can result in changes of heart rate-corrected QT (...

Detailed Description

Intraperitoneal insufflation of carbon dioxide may affect the sympathetic activity that leads to changes in ventricular re-polarization. This in turn can result in changes of heart rate-corrected QT (...

Eligibility Criteria

Inclusion

  • Patients undergoing robot-assisted laparoscopic prostatectomy
  • Age more than 19 years

Exclusion

  • Preoperative electrocardiography (ECG) abnormalities, including a QTc interval of \>500 ms, ventricular conduction abnormalities, or arrhythmias
  • History of cardiac disease such as pacemaker insertion, unstable angina
  • Use of antiarrhythmic agents or medications that are known to prolong the QTc interval
  • Abnormal levels of preoperative serum electrolyte

Key Trial Info

Start Date :

August 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 12 2020

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT03232125

Start Date

August 1 2017

End Date

June 12 2020

Last Update

August 25 2020

Active Locations (1)

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1

Professor, Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University College of Medicine

Seoul, South Korea, 03722