Status:

COMPLETED

Clinical Benefit of a Mouthrinse for the Treatment of Dentine Hypersensitivity

Lead Sponsor:

InQpharm Group

Conditions:

Dentin Sensitivity

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This study is to evaluate the benefit and tolerability of a Mouthrinse (IQP-OLP-101) in the treatment of dentine hypersensitivity.

Eligibility Criteria

Inclusion

  • At least one hypersensitive tooth in everyday life after PAV 1 in-office visit
  • At least one hypersensitive tooth in everyday life with a regular pain perception of at least 2 times per week after PAV 1 visit
  • At least one tooth with dentine hypersensitivity to air stimulation → VAS ≥ 40mm at study entry
  • Any sensitive tooth showing exposure of cervical dentine (gum recession) and no acute signs of caries on the exposed root
  • For subjects entering the study at stage PAR-control: good healing of the periodontal surgery site, cause of pain must not be the result of the periodontal surgery
  • Age ≥ 18 years and ≤ 75 years
  • Willing and able to attend the on-study visits
  • Willing and able to understand and to follow the study procedures and instructions
  • Good oral hygiene throughout the study
  • Written informed consent before participation in the study
  • Subjects have undergone dental hygiene treatment immediately prior to study inclusion (except subjects entering the study at stage PAR-control)

Exclusion

  • Hypersensitivity only due to sweets
  • Allergic reactions to any ingredients of InQpharm Mouthrinse e.g. chlorhexidine, zinc lactate
  • Professional desensitizing therapy during the previous 3 months; GLUMA (glutaraldehyde/hydroxyethyl methacrylate) desensitizer application within 6 months
  • Chronic systemic anti-inflammatory and analgesic medications
  • Systemic disorders causing or predisposing to dental (e.g. dry mouth, reflux, eating disorders, etc.)
  • Teeth or supporting structures with any other painful pathology or defect
  • Subject with poor health conditions
  • Concurrent participation in another clinical trial
  • Pregnant or lactating women

Key Trial Info

Start Date :

August 25 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 7 2017

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03232255

Start Date

August 25 2017

End Date

December 7 2017

Last Update

January 3 2018

Active Locations (1)

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1

Praxisklinik ORS

Fellbach, Germany, 70736