Status:
COMPLETED
Dexmedetomidine and Neuroprotection in Children Undergoing General Anesthesia
Lead Sponsor:
Seoul National University Hospital
Conditions:
Dexmedetomidine
Eligibility:
All Genders
1-3 years
Phase:
NA
Brief Summary
Neuroapoptosis is induced by the administration of anesthetic agents to the young brain. Recent studies showed that the a2-adrenoceptor agonist, dexmedetomidine plays a trophic role during development...
Detailed Description
GFAP measure
Eligibility Criteria
Inclusion
- children undergoing general anesthesia longer than 3 hours
Exclusion
- past history of anesthesia
- cardiopulmonary bypass
- preexisting neurocognitive dysfunction
- abnormalities of liver profile (aspartate transaminase \> 40 unit/L, alanine aminotransferase \> 40 unit/L)
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 5 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03234660
Start Date
September 1 2017
End Date
October 5 2019
Last Update
January 2 2020
Active Locations (1)
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1
SNUH
Seoul, Jongro Gu, South Korea, 15710