Status:
WITHDRAWN
Microvascular and Metabolic Effects of High-intensity Interval Exercise Training
Lead Sponsor:
National Institute of Cardiology, Laranjeiras, Brazil
Conditions:
Obesity
Overweight
Eligibility:
FEMALE
30-50 years
Phase:
NA
Brief Summary
The study investigates the effects of high intensity interval training (HIIT) versus continuous training (CT), combined or not with fasting, on capillary density, microvascular function, cardiometabol...
Detailed Description
Physical inactivity and increased caloric intake play important roles in the pathophysiology of obesity. Increases of physical activity and modifications of eating behaviors are first-line interventio...
Eligibility Criteria
Inclusion
- Female gender
- Age≥ 30 years and ≤50 years
- Premenopausal status
- Body mass index \>25 kg/m2
- At least one of the following:
- waist circumference ≥80 cm (women); triglycerides ≥150 mg/dl or treatment for this lipid abnormality; High density-lipoprotein cholesterol \<50 mg/dl (women), or treatment for this abnormality; fasting plasma glucose ≥100 mg/dl
Exclusion
- Any cardiovascular disease, including systemic hypertension
- Diabetes mellitus
- Chronic pulmonary disease
- Any systemic disease or condition that might reduce the adherence or tolerance to exercise or fasting
- Orthopedic or neurologic conditions that might impair exercise training
- Pregnancy or breastfeeding
- Abnormalities elicited at exercise treadmill testing that preclude the initiation of exercise training
- Current engagement in any exercise training protocol
Key Trial Info
Start Date :
February 20 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2021
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03236285
Start Date
February 20 2018
End Date
October 1 2021
Last Update
March 13 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Institute of Cardiology, Ministry of Health, Brazil
Rio de Janeiro, Brazil, 22240-006