Status:
COMPLETED
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor: Comparing 125 mL/h Versus 250 mL/h Bolus Delivery Flow
Lead Sponsor:
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Conditions:
Labor Pain
Eligibility:
FEMALE
18-55 years
Phase:
NA
Brief Summary
At Mount Sinai Hospital, epidural analgesia for labor pain is delivered by programmed intermittent epidural bolus (PIEB), in combination with pushes of medication activated by the patient, a technique...
Detailed Description
PIEB is a novel technique, which provides better analgesia and less motor block; however, the ideal regimen has not been established. To optimize the PIEB regimen, the investigators have conducted sev...
Eligibility Criteria
Inclusion
- ASA II or III
- Term pregnancy (gestational age ≥ 37 weeks)
- Nulliparous
- Singleton pregnancy with vertex presentation
- Active labour defined as occurring regular uterine contractions at least every 5 minutes with progressive cervical dilatation
- Verbal Numerical Rating Score (VNRS) greater than 5 at requiring epidural analgesia (VNRS 0-10)
- Cervical dilation between 2 and 5 cm
Exclusion
- Any contraindication to epidural analgesia
- Accidental dural puncture
- Drug allergy to lidocaine, bupivacaine or fentanyl
- Use of pharmacological analgesics within the last 4 hours
- Patient refusal to participate in the trial
Key Trial Info
Start Date :
August 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 23 2020
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03236298
Start Date
August 1 2017
End Date
January 23 2020
Last Update
March 20 2020
Active Locations (1)
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1
Mount Sinai Hospital
Toronto, Ontario, Canada, M5G1X5