Status:
COMPLETED
Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury
Lead Sponsor:
Oladipupo Olafiranye, MD, MS
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Contrast-induced Acute Kidney Injury
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This a prospective, double-blind, sham-controlled, randomized clinical trial to study the effects of remote ischemic preconditioning on acute kidney injury, vascular and renal biomarkers in patients w...
Detailed Description
The BRICK study is a prospective, double-blind, sham-controlled, randomized clinical trial in patients with non-ST elevation myocardial infarction and unstable angina undergoing coronary angiography a...
Eligibility Criteria
Inclusion
- Patient with non-ST elevation myocardial infarction or unstable angina
- Referral for cardiac catheterization and percutaneous coronary intervention
- Contrast-induced acute kidney injury risk score of ≥11
Exclusion
- Inability to give informed consent
- unstable blood pressure (systolic blood pressure \> 200 or \<90 mmHg)
- History of allergy to contrast media
- Peripheral vascular disease of upper limb
- Renal disease requiring dialysis
- Placement of arteriovenous fistula and arteriovenous graft
Key Trial Info
Start Date :
March 6 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2024
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT03236441
Start Date
March 6 2018
End Date
February 28 2024
Last Update
January 9 2025
Active Locations (2)
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1
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15213
2
VA Pittsburgh Healthcare System
Pittsburgh, Pennsylvania, United States, 15213