Status:
UNKNOWN
Magnetic Resonance Imaging in High Risk Patients for the Development of Diffuse Idiopathic Skeletal Hyperostosis (DISH)
Lead Sponsor:
HaEmek Medical Center, Israel
Collaborating Sponsors:
The Chaim Sheba Medical Center
Conditions:
Hyperostosis, Diffuse Idiopathic Skeletal
Metabolic Syndrome
Eligibility:
All Genders
40-49 years
Phase:
NA
Brief Summary
Diffuse idiopathic skeletal hyperostosis (DISH) is a poorly understood, systemic condition characterized by progressive calcification and ossification of ligaments and entheses. The current classifica...
Detailed Description
Patient's selection- Patients will be recruited from obesity/metabolic/diabetes clinics and from bariatric surgeries clinics. All patients will have the diagnosis of metabolic syndrome National Choles...
Eligibility Criteria
Inclusion
- Meet the NCEP 3 criteria for metabolic syndrome and/or have type 2 diabetes mellitus (9).
- Age 40-49 years
Exclusion
- ESR and CRP levels above common levels adjusted for age, gender, and weight.(I have ref for the determination of common CRP levels).
- Positive HLA B-27 Personal or family history of Spondyloarthritis, psoriasis or inflammatory arthritis (past or present) Inflammatory back pain as defined by the ASAS definition (age at onset \<40y, insidious onset, improvement with exercise, no improvement with rest, pain at night with improvement upon getting up = IBP if 4/5 items are present) (Ref) History of uveitis Plain radiographs with evidence for DISH
Key Trial Info
Start Date :
August 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2022
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03237455
Start Date
August 1 2018
End Date
December 30 2022
Last Update
August 9 2022
Active Locations (1)
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1
HaEmek MC and Chaim Sheba MC
Afula, Israel, 18101