Status:
COMPLETED
Functional Chewing Gum in Reduction of Gingival Inflammation
Lead Sponsor:
University of Maryland, Baltimore
Conditions:
Gingivitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of this prospective randomized 3-month double-blinded single center study is to determine whether a chewing gum device with food additive chitosan, will aid in reducing gingival inflammation b...
Detailed Description
Periodontal disease remains a prevalent and preventable disease in man. Plaque bacterial biofilm remains the primary etiologic agent of disease; colonization of non-shedding tooth surfaces greatly con...
Eligibility Criteria
Inclusion
- Mild-moderate gingivitis
- Minimum of 20 natural teeth
Exclusion
- Significant alveolar bone loss as evidenced by Bite-wings (\>3.0 mm cementoenamel junction to bone)
- Requirement for antibiotic pre-medication prior to dental procedures
- Systemic antibiotic use in past 14 days to current.
- Use of oral contraceptives
- Use of anti-inflammatory (NSAIDs) or in past 14 days.
- Use of anticoagulant therapy or in past 14 days.
- Poorly controlled diabetes (HbA1c \> 7.9%)\*
- Smoking
- Pregnancy
- Use of any oral rinses such as, but not limited to chlorhexidine, essential oils, cetylpyridinium chloride during the study.
Key Trial Info
Start Date :
January 31 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2020
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT03237624
Start Date
January 31 2018
End Date
January 31 2020
Last Update
November 26 2024
Active Locations (1)
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1
University of Maryland School of Dentistry
Baltimore, Maryland, United States, 21201