Status:
UNKNOWN
MR-simulation in Radiotherapy for Prostate Cancer
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Conditions:
Cancer of the PROSTATE
Eligibility:
MALE
18+ years
Phase:
NA
Brief Summary
To assess the feasibility of acquiring an MR scan in the radiotherapy treatment position as part of the patient's radiotherapy pathway and incorporating the data into our radiotherapy planning systems...
Detailed Description
Conventional radiotherapy treatment planning uses computed tomography (CT) scans to provide an accurate 3-D picture of the local anatomy. This helps the planners to maximise the radiation dose deliver...
Eligibility Criteria
Inclusion
- Written, voluntary, informed consent
- Age ≥ 18
- ECOG Performance Status ≤ 2
- Life expectancy \> 12 months
- Histologically proven carcinoma of the prostate
- Radical radiotherapy +/- hormones indicated as the primary treatment modality
- Staging diagnostic MRI of the prostate need to be available for comparison.
- Adequate organ function and absence of other major concurrent illness, allowing
Exclusion
- Inability to provide informed consent
- Impaired renal function (serum creatinine of \> 200)
- Severely impaired liver function
- Patients with allergies or contra-indications to the gadolinium contrast agent that may be used in the study
- Severe claustrophobia or inability to tolerate MRI scans
- General contra-indications to MRI including cardiac pacemakers and defibrillators, metallic prosthetic devices, aneurysm clips and metal fragments in the eyes, as defined in MRI safety departmental protocols
- Serious inter-current conditions or other non-malignant illnesses that are uncontrolled or whose control may be affected by participation in this study
- Any patient who has urinary or faecal incontinence
- Status greater than or equal to 3
Key Trial Info
Start Date :
March 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03238170
Start Date
March 1 2017
End Date
June 1 2023
Last Update
March 18 2022
Active Locations (1)
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1
Guy's and St. Thomas' NHS Foundation Trust
London, United Kingdom, SE19RT