Status:
ACTIVE_NOT_RECRUITING
Mechanisms of Cardiac Dysfunction in HIV and the Effect of Statins: a Cardiac MRI Study
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH)
Conditions:
HIV Infections
Eligibility:
All Genders
40-75 years
Brief Summary
In this study, investigators plan to test whether statins can preserve and/or improve diastolic function among asymptomatic persons with HIV who are on anti-retroviral therapy. Both myocardial fibrosi...
Eligibility Criteria
Inclusion
- New enrollment in the REPRIEVE Trial
Exclusion
- clinical diagnosis of HFpEF or HFrEF, by subject report
- standard contraindications to MRI procedure based on MRI Patient Procedure Screening Form - including history of severe allergy to gadolinium
Key Trial Info
Start Date :
July 31 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 23 2026
Estimated Enrollment :
129 Patients enrolled
Trial Details
Trial ID
NCT03238755
Start Date
July 31 2017
End Date
April 23 2026
Last Update
November 21 2024
Active Locations (4)
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1
VA Medical Center-Los Angeles
Los Angeles, California, United States, 90073
2
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
3
UTSW Medical Center
Dallas, Texas, United States, 75235
4
University of Cape Town
Cape Town, South Africa