Status:
COMPLETED
Inspiratory Muscle Training in Difficult to Wean Patients
Lead Sponsor:
KU Leuven
Conditions:
Weaning Failure
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Prolonged mechanical ventilation secondary to weaning failure demands a significant amount of intensive care unit (ICU) resources, thus increasing the economic burden of public healthcare costs. One o...
Detailed Description
1\. Introduction. Weaning covers the entire process of liberating the patient from mechanical ventilation (MV) support and the endotracheal tube or tracheostomy. For the majority of mechanically-vent...
Eligibility Criteria
Inclusion
- Difficult and prolonged weaning patients
- Simple weaning patients
- Adequate oxygenation
- Febrile temperature \< 38ºC
- Hemodynamic stability
- Stable blood pressure
- No or minimal pressors
- No myocardial ischemia
- Adequate hemoglobin and mentation
- Resolution of disease acute phase
- Able to follow simple verbal commands related to IMT
- Mechanically ventilated via a tracheostomy or endotracheal tube
Exclusion
- Pre-existing neuromuscular disease
- Agitation
- Hemodynamically instable (arrhythmia, decompensated heart failure, coronary insufficiency)
- Hemoptysis
- Diaphoresis
- Spinal cord injury above T8
- Use of any type of home MV support prior to hospitalization
- Skeletal pathology that impairs chest wall movements
- Poor general prognosis or fatal outcome
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2023
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03240263
Start Date
September 1 2017
End Date
October 1 2023
Last Update
October 9 2024
Active Locations (1)
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1
University Hospital Leuven
Leuven, Belgium, 3000