Status:
COMPLETED
Triclosan Toothpaste as a Preventive Strategy of Mucositis in Smokers
Lead Sponsor:
Paulista University
Conditions:
Dental Implants
Cigarette Smoking
Eligibility:
All Genders
30-70 years
Phase:
NA
Brief Summary
The purpose of this trial was to determine the effect of a triclosan-containing toothpaste in the clinical parameters and in the profile of osteo-immunoinflammatory mediators in the peri-implant crevi...
Detailed Description
This study was designed as double-blind, randomized, crossover study to evaluate the influence of a triclosan-containing toothpaste in the profile of osteo-immunoinflammatory mediators in the PICF of ...
Eligibility Criteria
Inclusion
- 30 years old or more
- Patients should be smokers (more than 10 cigarettes/day, for at least 2 years),
- present at least a 2-stage unitary screwed implant-supported single-unit crown in the molar or pre-molar region implant connection should be external hexagonal and the implants should be in function at least 12 months
- width of keratinized tissue \> 2mm around implants
- The peri-implant tissue should be healthy \[probing depth (PD) \<4mm with no bleeding on probing (BoP) and no evidence of radiographic bone loss beyond bone remodeling (AAP 2013).
- Patients should be periodontally healthy and present full mouth plaque scores and bleeding score \< 20%.
Exclusion
- pregnancy
- lactation
- systemic conditions r that could affect the progression of peri-implant diseases and bone metabolism (e.g., immunologic disorders)
- use of long-term administration of anti-inflammatory and immunosuppressive medications antibiotic therapies in the previous 6 months
- individuals that required bone grafts before or alongside the implant surgery history of previous regenerative procedures in the area treated with implant therapy.
Key Trial Info
Start Date :
July 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2015
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT03241407
Start Date
July 1 2013
End Date
April 30 2015
Last Update
August 7 2017
Active Locations (1)
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1
School of Dentistry - Paulista University UNIP
São Paulo, São Paulo, Brazil, 052