Status:
COMPLETED
Novel PAradigm to Improve Inflammatory Burden in ESRD (rePAIR): A Pilot and Feasibility Randomized Controlled Trial
Lead Sponsor:
UConn Health
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Chronic Periodontitis
End Stage Renal Disease
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
The goal of this project is to assess repeated and ongoing oral care and the way it may affect inflammation and quality of life in hemodialysis patients. Two treatment groups will be compared: * 1\) ...
Eligibility Criteria
Inclusion
- Patient must be referred by nephrologist
- Patient must be diagnosed with ESRD and on Hemodialysis
- life expectancy more than one year
- at least 21 years of age
- 12 or more teeth
- must meet the Periodontal diagnosis criteria (The diagnosis of periodontitis is based on the definition of moderate periodontitis with at least 2 sites with CAL≥4mm or at least 2 sites with PD≥5mm not on the same tooth (Page and Eke 2007).)
Exclusion
- Anticipating a kidney transplant
- AIDS
- Active malignancy
- Poor adherence to hemodialysis
- Dementia
- Currently prescribed anti-inflammatory medication
- Temporary catheter for dialysis access
- Gum disease treatment within the last year
Key Trial Info
Start Date :
November 7 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2020
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT03241511
Start Date
November 7 2017
End Date
December 1 2020
Last Update
June 5 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Connecticut Health Center
Farmington, Connecticut, United States, 06030-1710