Status:

UNKNOWN

Assessment of Patients With Hepatitis C Virus Related Liver Cirrhosis After Sustained Response to Direct Acting Anti Viral Drugs.

Lead Sponsor:

Assiut University

Conditions:

Hepatitis C

Liver Cirrhosis

Eligibility:

All Genders

18+ years

Brief Summary

Hepatitis C Virus (HCV) infection is a major global health challenge; it is estimated that more than 80 million people are chronically infected worldwide, with 3-4 million new infections and 350,000 d...

Detailed Description

In 2015, a national Egyptian health issue survey was conducted to describe the prevalence of hepatitis C virus infection. The prevalence of hepatitis C virus antibody was found to be 10.0% and that of...

Eligibility Criteria

Inclusion

  • Age: ≥ 18 years.
  • Disease status: patients with hepatitis C Virus related liver cirrhosis child A\& B (scores 5-9).
  • Previous treatment: treatment naïve and treatment experienced.
  • HCV RNA: Negative at any point between 12-24 weeks post treatment to confirm successful eradication of the virus.
  • Negative HBsAg and HIV antibody.
  • Normal kidney function test

Exclusion

  • Child C liver cirrhosis (Child score ≥ 10).
  • HCV coinfection with HBV or HIV.
  • Patients with high risk of infection (I.V drug users, patients with blood disease requiring blood transfusion).

Key Trial Info

Start Date :

December 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2019

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03241823

Start Date

December 1 2017

End Date

March 1 2019

Last Update

August 8 2017

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Assuit Unit of Treatment of Viral Hepatitis.

Asyut, Egypt, 71111