Status:
COMPLETED
Comparing the Effects of Lactated Ringers and Normal Saline in Acute Pancreatitis
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Collaborating Sponsors:
Children's National Research Institute
Children's Hospital of The King's Daughters
Conditions:
Pancreatitis
Eligibility:
All Genders
Up to 18 years
Phase:
NA
Brief Summary
Acute pancreatitis is increasingly common diagnosis in children. Most of the guidelines related to the details of management of acute pancreatitis are extrapolated from the adult literature. There is ...
Detailed Description
Acute pancreatitis represents inflammation of the pancreas that has been well identified in the literature for several centuries. However, the phenomenon has only relatively recently gained prominence...
Eligibility Criteria
Inclusion
- Patients aged 0-18 years diagnosed with acute pancreatitis in the emergency department or inpatient ward at Children's Hospital of The King's Daughters or one of the affiliated institutions participating in the study.
Exclusion
- Patients greater than 18 years of age
- Patients who are not diagnosed with acute pancreatitis
- Patients who have any previous history of acute pancreatitis, past medical history of underlying illness including congenital heart disease, chronic lung disease, or renal failure
- Patients who have any of the following: hyperkalemia, systemic acidosis, acute dehydration, extensive tissue breakdown, adrenal insufficiency, concomitant use of potassium-sparing diuretics, use of extended-release preparations in patients with esophageal compression caused by an enlarged left atrium, hypersensitivity to sodium chloride, hypernatremia, or fluid retention
- Patients who are pregnant females
- Patients who have additional comorbidities at time of admission that would prevent adequate treatment with the methods described above will be excluded
Key Trial Info
Start Date :
December 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 23 2020
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT03242473
Start Date
December 1 2014
End Date
October 23 2020
Last Update
August 17 2021
Active Locations (3)
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1
Children's National Health System
Washington D.C., District of Columbia, United States, 20010
2
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229
3
Children's Hospital of The King's Daughters
Norfolk, Virginia, United States, 23507