Status:

UNKNOWN

Cervical Morphological Changes on Pregnancy Outcome

Lead Sponsor:

The Second Affiliated Hospital of Chongqing Medical University

Conditions:

Pregnancy Outcome

Eligibility:

FEMALE

21-45 years

Brief Summary

This study aims to assess how the proportion of the cervical volume/length removed during treatment for cervical intraepithelial neoplasia (CIN) varies and whether this correlates to the pregnancy dur...

Detailed Description

The high peak age of the Cervical intraepithelial neoplasia (CIN)patients was from 25 to 35 years old, which is the best women of childbearing age, Standard treatment for CIN is called Loop electrosur...

Eligibility Criteria

Inclusion

  • Having fertility requirements,antecedent biopsy read as
  • cervical intraepithelial neoplasia (CIN) grade 2 or 3 or microinvasive cancer
  • adenocarcinoma in situ
  • persistent CIN 1
  • antecedent pap read as
  • high grade squamous intraepithelial lesion
  • atypical glandular cells
  • persistent low grade squamous intraepithelial lesion

Exclusion

  • anatomy unsuitable for safe office loop excision based on operator judgement
  • inability to tolerate procedure under local anesthesia
  • pregnancy
  • age less than 21 years
  • refusal of consent
  • prisoner
  • mental incapacity
  • anticoagulant or antiplatelet therapy, or known bleeding diathesis
  • use of analgesics other than over the counter medications(OTC meds include NSAIDS or Tylenol) within 7 days of scheduled LEEP.

Key Trial Info

Start Date :

September 15 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2021

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT03242746

Start Date

September 15 2017

End Date

September 1 2021

Last Update

June 27 2018

Active Locations (1)

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2ndChongqingMU

Yuzhong, Chongqing Municipality, China, 023