Status:
COMPLETED
The Aortic Valve DECalcification (AVADEC) Trial
Lead Sponsor:
Axel Diederichsen
Conditions:
Aortic Valve Stenosis
Multidetector Computed Tomography
Eligibility:
MALE
65-75 years
Phase:
NA
Brief Summary
Aortic stenosis is a common heart valve disease and due to the growing elderly population the prevalence is increasing. The disease is progressive with increasing calcification of the valve cusps. A f...
Eligibility Criteria
Inclusion
- Participants in the Danish Cardiovascular Screening Trial (Trials. 2015 Dec 5;16:554) with an aortic valve calcification score above 300, but without aortic valve stenosis are eligible.
Exclusion
- Known aortic valve disease (peak velocity ≥3.0 m/s)
- History of venous thrombosis or other coagulation disorders or use of vitamin K antagonists
- Disorders of calcium and phosphate metabolism
- A life-expectancy \< 5 years
Key Trial Info
Start Date :
January 12 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2021
Estimated Enrollment :
389 Patients enrolled
Trial Details
Trial ID
NCT03243890
Start Date
January 12 2018
End Date
May 1 2021
Last Update
September 29 2022
Active Locations (1)
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1
Department of Cardiology, Odense University Hospital
Odense, Odense C, Denmark, DK-5000