Status:

COMPLETED

HEMOCC Study. Hemostasis in Cirrhotic Children.

Lead Sponsor:

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Conditions:

Esophageal and Gastric Varices

Child, Only

Eligibility:

All Genders

4-50 years

Phase:

NA

Brief Summary

Prospective investigations into the role of hemostatic factors in the risk of variceal bleeding among children with chronic liver disease (thromboelastometry e.g) is still required. A better understan...

Detailed Description

The investigators aim to start a prospective and observational study over a 2 years period. First, the investigators will identify all children suffering from cirrhosis irrespective of underlying eti...

Eligibility Criteria

Inclusion

  • Children suffering from decompensated cirrhosis and needing an orthotopic liver transplantation
  • Children suffering from a compensated cirrhosis (compensated cirrhosis with kasai surgery in biliary atresia patients e.g) or from portal hypertension without cirrhosis (portal vein thrombosis e.g)
  • Each patient will have a comprehensive assessment of portal hypertension (abdominal US-Doppler and upper gastrointestinal endoscopy) and hemostasis

Exclusion

  • No underlying disease which can alter hemostasis (hemophilia, sepsis…)
  • No medication which can alter hemostasis (aspirin, anti-inflammatory drugs,…)

Key Trial Info

Start Date :

October 18 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 15 2017

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03244332

Start Date

October 18 2013

End Date

July 15 2017

Last Update

August 9 2017

Active Locations (1)

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Cliniques Universitaires Saint-Luc

Brussels, Belgium, 1200