Status:

COMPLETED

Tranexamic Acid in Cyanotic Heart Defects

Lead Sponsor:

Assiut University

Conditions:

Postoperative Hemorrhage

Eligibility:

All Genders

2-12 years

Phase:

PHASE2

Brief Summary

The use of antifibrinolytic agents such as to reduce blood loss in congenital cardiac surgery has been described in many studies

Detailed Description

40 patients in each one of the three groups; In control group will receive normal saline, Intravenous Tranexamic acid group received 50 mg / kg intravenousely followed by of 1 mg/kg/hr.for six hours. ...

Eligibility Criteria

Inclusion

  • 2 to 12 years cyanotic cardiac disease with cardio pulmonary bypass

Exclusion

  • Previous cardiac surgery any operation within 48 hr., previous inotropes or mechanical vention aprotinin exposure Liver or renal impairment Coagulation or hemostatic dysfunction within the last 7 days before surgery.

Key Trial Info

Start Date :

January 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2017

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT03244423

Start Date

January 1 2009

End Date

August 1 2017

Last Update

January 31 2018

Active Locations (1)

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1

Faculty of Medicine

Asyut, Egypt, 74111