Status:
COMPLETED
Biomarker-guided Implementation of the AKI Bundle
Lead Sponsor:
University Hospital Muenster
Collaborating Sponsors:
European Society of Intensive Care Medicine
Conditions:
Acute Kidney Injury (Nontraumatic)
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
There is no specific therapy for acute kidney injury. It is presumed that supportive measures improve the care and outcome of patients with acute kidney injury. The investigators hypothesize that the...
Eligibility Criteria
Inclusion
- Adult patients undergoing cardiac surgery with cardiopulmonary bypass (CPB)
- Urinary \[TIMP-2\] \* \[IGFBP7\] \>= 0.3 4h after CPB
- Written informed consent
Exclusion
- Preexisting AKI (stage 1 and higher)
- Patients with cardiac assist devices (ECMO, LVAD, RVAD, IABP)
- Pregnancy, breastfeeding
- Known (Glomerulo-)-Nephritis, intersstitial nephritis or vasculitis
- CKD with eGFR \< 20 mL/min
- Dialyses dependent CKD
- Prior kidney transplant within the last 12 months
Key Trial Info
Start Date :
November 2 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 26 2020
Estimated Enrollment :
280 Patients enrolled
Trial Details
Trial ID
NCT03244514
Start Date
November 2 2017
End Date
January 26 2020
Last Update
February 19 2020
Active Locations (12)
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1
CHU Brugmann, Intensive Care Medicine
Brussels, Belgium, 1020
2
AZ Maria Middelares
Ghent, Belgium, 9000
3
Universitair Ziekenhuis Gent
Ghent, Belgium, 9000
4
Universitätsklinikum Bergmannsheil Bochum
Bochum, Germany, D-44789