Status:

COMPLETED

International BPA Registry

Lead Sponsor:

International CTEPH Association

Conditions:

Chronic Thromboembolic Pulmonary Hypertension

CTEPH

Eligibility:

All Genders

Brief Summary

The International Balloon Pulmonary Angioplasty (BPA) Registry is a prospective, multi-center, long-term observational project. Scheduled to start data collection in Q4 2017, the registry will run for...

Eligibility Criteria

Inclusion

  • Diagnosis with CTEPH according to the following criteria:
  • Mean PAP ≥ 25mmHg at rest; or if mean PAP \< 25mmHg at rest, have exercise limitations from chronic thromboembolic disease
  • Abnormal ventilation perfusion lung scanning (VQ) scan, pulmonary angiogram, computer tomographic pulmonary angiogram, or magnetic resonance pulmonary angiogram confirming chronic thromboembolic disease as recommended by standard guidelines
  • Treatment with anticoagulation for ≥ 3 months before diagnosis of CTEPH
  • Naïve to BPA treatment
  • Scheduled to undergo their first BPA session ≥ 1 day after enrollment. Enrollment is defined as date the consent is signed by the patient. Enrollment must occur before any BPA session
  • Willing to provide informed consent

Exclusion

  • BPA treatment prior to enrollment
  • Pulmonary hypertension cause other than World Health Organization (WHO) group IV (CTEPH)
  • Targeted BPA treatment lesion other than from WHO group IV (CTEPH)

Key Trial Info

Start Date :

March 2 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 31 2022

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT03245268

Start Date

March 2 2018

End Date

March 31 2022

Last Update

June 10 2022

Active Locations (18)

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Page 1 of 5 (18 locations)

1

University of California San Diego

La Jolla, California, United States, 92093

2

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

3

Mayo Clinic

Rochester, Minnesota, United States, 55905

4

Cleveland Clinic

Cleveland, Ohio, United States, 44195