Status:
COMPLETED
Cardiac Function and Metabolism in Young Adults Born Premature (PET-MRI)
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
National Institutes of Health (NIH)
American Heart Association
Conditions:
Infant,Premature
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
The purpose of this research is to determine the effect of premature birth on later heart function and metabolism.
Detailed Description
The purpose of this study is to determine the effects of premature birth on cardiac function, cardiac metabolism, and oxidative stress in a cohort of young adults born prematurely using cardiac positr...
Eligibility Criteria
Inclusion
- National Lung Project Cohort only- birth weight \<1500g and a gestational age \<36 weeks
- Adults born preterm (Non-National Lung Project) only- gestational age ≤32 weeks OR birth weight ≤ 3lbs 5oz
- Healthy Controls only- No personal history of known cardiovascular or pulmonary disease
Exclusion
- Metabolic Disorders that would affect Fludeoxyglucose uptake
- Contraindications to positron emission tomography and/or magnetic resonance imaging
- Pregnancy, if a female of child-bearing potential
- A personal history of Type I or Type II diabetes
Key Trial Info
Start Date :
September 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 26 2020
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT03245723
Start Date
September 20 2017
End Date
February 26 2020
Last Update
February 4 2021
Active Locations (1)
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1
UW Madison
Madison, Wisconsin, United States, 53792