Status:
COMPLETED
Characteristics of Obstructive Sleep Apnea Syndrome Related Hypertension and the Effect of Continuous Positive Airway Pressure Treatment on Blood Pressure
Lead Sponsor:
Huai'an No.1 People's Hospital
Collaborating Sponsors:
The First Affiliated Hospital with Nanjing Medical University
Conditions:
Hypertension Secondary
Eligibility:
All Genders
18-70 years
Brief Summary
Obstructive sleep apnea syndrome (OSAS) causes nocturnal chronic intermittent hypoxia (CIH) that contributes to the development of hypertension. CIH profiles, including the its length, speed and inten...
Detailed Description
Nocturnal BP was continuously monitored via measurement of pulse transmit time (PTT). The value of apnea-related systolic BP elevation (△BP) was used to reflect short-term BPV. Beat-to-beat RR interva...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- BP≤180/110mmHg,but≥140/90mmHg
- without taking oral antihypertensive drugs. Exclusion criteria.
- (1) patients who had been hospitalized for cardiac or respiratory exacerbation\<6wk prior to recruiting; (2) with autonomic nervous system diseases or endocrine disorders which might influence BP; (3) unwilling to participate in the study.
Exclusion
Key Trial Info
Start Date :
April 3 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2021
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT03246022
Start Date
April 3 2018
End Date
December 30 2021
Last Update
March 29 2022
Active Locations (1)
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1
Department Of Respiratory Medicine,Huai'an First People's Hospital,Nanjing Medical University
Huai'an, Jiangsu, China, 223300