Status:
TERMINATED
Oral Olanzapine Versus Haloperidol or Diazepam
Lead Sponsor:
The University of Hong Kong
Collaborating Sponsors:
Queen Elizabeth Hospital, Hong Kong
Conditions:
Acute Agitation
Behavioural Emergency
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether oral olanzapine is safer (fewer adverse events) and more effective (shorter time to sedation) than conventional haloperidol or diazepam when used in t...
Detailed Description
1. Investigate oral use of sedating drugs within a predominantly Chinese population, to address this void in international literature impacting the management of acute agitation. 2. The multi-centre R...
Eligibility Criteria
Inclusion
- Accident \& Emergency Department patients
- Requiring oral drug sedation (as determined by an emergency clinician) will be enrolled.
Exclusion
- known hypersensitivity or contraindication to the study drugs
- reversible aetiology for agitation (e.g. hypotension, hypoxia, hypoglycaemia)
- known pregnancy
- acute alcohol withdrawal
- refusal to take oral medication
- patients from correctional facilities
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT03246620
Start Date
September 1 2017
End Date
June 1 2018
Last Update
November 4 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Queen Elizabeth Hospital
Hong Kong, Hong Kong