Status:
RECRUITING
Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons
Lead Sponsor:
Odense University Hospital
Collaborating Sponsors:
University of Southern Denmark
Odense Patient Data Explorative Network
Conditions:
Psoriatic Arthritis
Enthesitis
Eligibility:
All Genders
18-70 years
Brief Summary
Tendon pathologies (enthesitis) are a characteristic component of psoriatic arthritis (PsA), and are observed in 35% to 50% of PsA patients. The Achilles tendon is one of the most commonly affected si...
Detailed Description
Aim: The main objective of the IMPAACT study is to describe the histological findings of PsA Achilles enthesitis, and to a) Characterize and b) Quantify the immune-competent cell presence in tendon sp...
Eligibility Criteria
Inclusion
- Fulfilling the CASPAR criteria
- Insertional Achilles tendon pain
- Ultrasonic findings of inflammatory disease at the painful Achilles tendon insertion (= enthesitis) defined as abnormally hypoechoic (loss of normal fibrillar architecture) and/or thickened tendon at its bony attachment, seen in two perpendicular planes that may exhibit a Doppler signal or bony changes, including enthesophytes, and erosions.
Exclusion
- Other inflammatory rheumatic diseases than PsA
- Ultrasonic signs of complete rupture of the Achilles tendon
- Not wishing to participate or not suited for project evaluation
Key Trial Info
Start Date :
August 21 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2027
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03248284
Start Date
August 21 2017
End Date
March 31 2027
Last Update
December 5 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Odense University Hospital
Odense, Denmark, 5000
2
Diagnostic Center
Silkeborg, Denmark