Status:

COMPLETED

Investigation of Anti-obesity Properties of Lactobacillus Sakei in Obese Human Subjects

Lead Sponsor:

Seoul National University Bundang Hospital

Conditions:

Obesity

Eligibility:

All Genders

20-65 years

Phase:

NA

Brief Summary

In this study, we are going to investigate the efficacy of Lactobacillus Sakei on reduction of fat mass assessed by DEXA compared to plaebo.

Detailed Description

We are going to enroll subjects whose BMI is equal to higher than 25, and randomly assigned study material or placebo at 1:1 ratio. The treatment duration is 12 weeks.

Eligibility Criteria

Inclusion

  • age 20-65 years
  • BMI equal to higher than 25 kg/m2

Exclusion

  • under anti-obesity medication
  • uncontrolled diabetes
  • uncontrolled hypertension
  • any medications can influence to body weight such as thiazolidinedione, GLP-1 analogue, SGLT2 inhibitor, diuretics
  • thyroid function test abnormality
  • malignancy within 5 years
  • immune compromised hosts or under immune suppressants
  • antibiotics or probiotics withing 2 weeks
  • any intervention to reduce body weight within 6 months

Key Trial Info

Start Date :

August 10 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 10 2018

Estimated Enrollment :

114 Patients enrolled

Trial Details

Trial ID

NCT03248414

Start Date

August 10 2016

End Date

September 10 2018

Last Update

September 11 2018

Active Locations (1)

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Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea, 463-707