Status:

COMPLETED

Glycemic Index of Table Grape Varietals

Lead Sponsor:

University of California, Davis

Conditions:

Healthy

Eligibility:

All Genders

21-75 years

Phase:

NA

Brief Summary

Investigate the postprandial glycemic responses of healthy individuals when consuming commercially available table grape varietals or grape juice, compared to a standard amount of glucose.

Detailed Description

The study aims to investigate the postprandial glycemic responses of healthy individuals when consuming commercially available table grape varietals, compared to a standard amount of glucose. The stud...

Eligibility Criteria

Inclusion

  • Healthy men and women
  • 21-75 years of age
  • BMI range 20-35

Exclusion

  • adults unable to consent, individuals who are not yet adults (children), pregnant women, and prisoners.
  • BMI of \>35 or morbid obesity.
  • Diagnosed type 1 or 2 diabetes, fasting blood glucose of \>125 mg/dl, or reported use of medications or supplements known to affect glucose metabolism (insulin, sulfonylureas, metformin, glucosidase inhibitors, thiazolidinedione, insulin sensitizers, GLP-1 mimetics).
  • Medications known to affect gastrointestinal motility (prokinetic agents such as reglan).
  • Renal, liver, pancreatic or cardiovascular disease, uncontrolled hypertension of \> 160/90, inflammatory bowel disease, disorders of esophageal and gastrointestinal motility, previous gastric resection or restriction procedures, autoimmune or immunologic disorders, anemia, breastfeeding women
  • Food allergy to grapes, or inability to tolerate gluten (celiac disease).
  • Poor venous access.
  • Smoking, illicit drug use, consuming \>7 alcoholic drinks per week.
  • Weight gain or loss of \> 5 kg within the prior 6 months.
  • Unwillingness to adhere to study protocol.

Key Trial Info

Start Date :

July 31 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 4 2018

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT03248609

Start Date

July 31 2017

End Date

June 4 2018

Last Update

May 2 2019

Active Locations (1)

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1

University of California Davis (Academic Surge, Ragle Human Nutrition Research Facility)

Davis, California, United States, 95616