Status:
COMPLETED
Efficacy of Intra-articular Neostigmine Versus Ketamine for Postoperative Analgesia in Arthroscopic Knee Surgery
Lead Sponsor:
Assiut University
Collaborating Sponsors:
Ghada Mohammed AboelFadl
Abualauon Elbiblawy
Conditions:
Postoperative Pain
Eligibility:
All Genders
18-50 years
Phase:
PHASE2
PHASE3
Brief Summary
To compare the efficacy of intra-articular administration of neostigmine versus ketamine as adjuvant analgesics after knee arthroscopy.
Detailed Description
Arthroscopic knee surgery is commonly performed as an outpatient procedure and is often associated with postoperative pain. Intraarticular (IA) local anesthetics (LA) are often used for prevention of ...
Eligibility Criteria
Inclusion
- One hundred patients aged above 18-50 years (ASA I or II) scheduled for elective arthroscopic knee surgery under intrathecal anaesthesia will be enrolled in our study.
Exclusion
- Absolute or relative contraindications for intrathecal anaesthesia,
- Allergy for the studied drugs.
- Patients having history of cardiovascular, cerebrovascular, and respiratory diseases,
- Patients receiving chronic pain treatment or hypertension treated with α methyldopa, clonidine or β adrenergic blockers were excluded from the study.
Key Trial Info
Start Date :
March 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03248648
Start Date
March 1 2017
End Date
December 1 2017
Last Update
January 15 2019
Active Locations (1)
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1
Assiut university hospitals
Asyut, Assiut Governorate, Egypt, Egypt, 715715