Status:

COMPLETED

Electronic Patient Reporting of Symptoms During Cancer Treatment

Lead Sponsor:

Alliance Foundation Trials, LLC.

Collaborating Sponsors:

Patient-Centered Outcomes Research Institute

University of North Carolina

Conditions:

Metastatic Cancer

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

The current study is designed to test nationally whether patients' outcomes and utilization of services can be improved through symptom monitoring via patient-reported outcomes between visits.

Detailed Description

This is a cluster RCT at approximately 50 sites where randomization will occur in a 1:1 ratio at the site level (not at the individual patient level). Therefore, approximately 25 sites will be randomi...

Eligibility Criteria

Inclusion

  • Adults (21+) with metastatic cancer of any type (EXCEPT leukemia or indolent \[slow growing\] lymphoma)
  • Receiving outpatient systemic cancer treatment for non-curative/palliative intent, including chemotherapy, targeted therapy, or immunotherapy.
  • Enrolled at any point in their treatment trajectory, meaning during any line of treatment, and at any point during a course or cycle of treatment.
  • Can understand English, Spanish, and/or Mandarin Chinese.

Exclusion

  • Cognitive deficits that would preclude understanding of consent form and/or questionnaires.
  • Current participation in a therapeutic clinical trial (because these often involve PRO questionnaires and intensive monitoring).
  • Patients being treated with curative intent (e.g., adjuvant chemotherapy for breast, lung, or ovarian cancer; primary curative therapy for testis cancer or lymphoma).
  • Receiving hormonal therapy only (e.g., tamoxifen or aromatase inhibitors in breast cancer; androgen deprivation therapy in prostate cancer; or octreotide in neuroendocrine cancers)
  • Indolent lymphomas (due to their prolonged time courses that may be minimally symptomatic).
  • Leukemias (time courses inconsistent with other tumor types in chronic and acute leukemias).
  • Does not understand English, Spanish, or Mandarin Chinese.

Key Trial Info

Start Date :

October 30 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 30 2023

Estimated Enrollment :

1197 Patients enrolled

Trial Details

Trial ID

NCT03249090

Start Date

October 30 2017

End Date

August 30 2023

Last Update

January 14 2025

Active Locations (45)

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Page 1 of 12 (45 locations)

1

Grand Valley Oncology

Grand Junction, Colorado, United States, 81505

2

Gwinnett Medical Center

Lawrenceville, Georgia, United States, 30046

3

Ingalls Memorial Hospital

Harvey, Illinois, United States, 60426

4

Illinois CancerCare-Peoria

Peoria, Illinois, United States, 61615