Status:

UNKNOWN

Corneal Thickness Changes With Scleral Contact Lenses

Lead Sponsor:

University of Waterloo

Collaborating Sponsors:

Bausch & Lomb Incorporated

Conditions:

Keratoconus

Healthy Controls

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to investigate changes in the corneal thickness of scleral contact lens wearers in a keratoconic (KC) population and compare to age-matched controls. The hypothesis is tha...

Detailed Description

The purpose of this study is to investigate changes in the corneal thickness of scleral contact lens wearers in a keratoconic (KC) population and compare to age-matched controls. The hypothesis is tha...

Eligibility Criteria

Inclusion

  • Inclusion Criteria (Test Group):
  • Had been diagnosed with keratoconus in at least one eye.
  • Is at least 18 years of age and has full legal capacity to volunteer.
  • Has read and understood the information consent letter.
  • Is willing and able to follow instructions and maintain the appointment schedule.
  • Inclusion Criteria (Control Group)
  • Had been NOT diagnosed with keratoconus in at least one eye.
  • Is at least 18 years of age and has full legal capacity to volunteer.
  • Has read and understood the information consent letter.
  • Is willing and able to follow instructions and maintain the appointment schedule.
  • Exclusion Criteria (Test Group):
  • Is using any topical medications that will affect ocular health.
  • Has any ocular pathology or severe insufficiency of lacrimal secretion (severe dry eyes) that would affect the wearing of contact lenses.
  • Has persistent, clinically significant corneal or conjunctival staining using sodium fluorescein dye.
  • Has any clinically significant lid or conjunctival abnormalities and active neovascularization.
  • Is aphakic.
  • Has undergone penetrating keratoplasty.
  • Is participating in any other type of eye related clinical or research study.
  • Has any known allergies or sensitivity to the diagnostic pharmaceuticals or products, such as fluorescein, used in this study.
  • Exclusion Criteria (Control Group):
  • Is using any topical medications that will affect ocular health.
  • Has any ocular pathology or severe insufficiency of lacrimal secretion (severe dry eyes) that would affect the wearing of contact lenses.
  • Has persistent, clinically significant corneal or conjunctival staining using sodium fluorescein dye.
  • Has any clinically significant lid or conjunctival abnormalities and active neovascularization.
  • Is aphakic.
  • Has undergone any corneal surgery.
  • Is participating in any other type of eye related clinical or research study.
  • Has any known allergies or sensitivity to the diagnostic pharmaceuticals or products, such as fluorescein, used in this study.

Exclusion

    Key Trial Info

    Start Date :

    June 22 2017

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2020

    Estimated Enrollment :

    40 Patients enrolled

    Trial Details

    Trial ID

    NCT03249233

    Start Date

    June 22 2017

    End Date

    December 1 2020

    Last Update

    April 10 2020

    Active Locations (1)

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    1

    University of Waterloo School of Optometry and Vision Science

    Waterloo, Ontario, Canada, N2L3G1

    Corneal Thickness Changes With Scleral Contact Lenses | DecenTrialz