Status:
COMPLETED
Work of Breathing Description in Neonates With Congenital Diaphragmatic Hernia in NAVA and in Conventional Ventilation.
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Hernia, DIaphragmatic, Congenital
Eligibility:
All Genders
1+ years
Phase:
NA
Brief Summary
Congenital diaphragmatic hernia (CDH) is a congenital malformation associated with significant mortality and respiratory morbidity, particularly related to prolonged mechanical ventilation. NAVA (Neur...
Eligibility Criteria
Inclusion
- Neonate admitted to neonatal intensive care beyond 34 weeks of amenorrhea
- With a diagnosis of congenital diaphragmatic hernia having undergone a repair surgery.
- Necessary invasive ventilatory support by conventional ventilation
- Informed and signed consent of parents (and / or holders of parental authority)
Exclusion
- Refusal of parents (and / or holders of parental authority) to participate in the study
- Contra-indication to the use of an oro or naso-gastric tube (oesophageal surgery)
- Child at risk of poor tolerance to the placement of the oesophageal pressure transducer (history of discomfort when placing a tube, weight \<1500g)
- Central or neuromuscular neurological pathology which may affect respiratory control
Key Trial Info
Start Date :
August 20 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 20 2021
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT03250793
Start Date
August 20 2018
End Date
January 20 2021
Last Update
September 4 2025
Active Locations (1)
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1
Service de Réanimation Néonatale- Hôpital Femme Mère Enfant- Hospices Civils de Lyon
Bron, France, 69500