Status:

COMPLETED

Switching TDF/FTC/EFV to TDF/FTC/RPV VS Continuing TDF/FTC/EFV in HIV Patients With Complete Virological Suppression

Lead Sponsor:

Mahidol University

Conditions:

Anti-Retroviral Agents

Efavirenz

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

According to the Thai National Guidelines for Treatment of HIV/AIDS 2014, the recommended first line ART regimen was 2 NRTIs backbone, TDF and FTC; plus 1 NNRTI, EFV, with RPV as an alternative one. M...

Detailed Description

According to the Thai National Guidelines for Treatment of HIV/AIDS 2014, the recommended first line ART (Anti-retroviral therapy) regimen was 2 NRTIs (nucleoside reverse transcriptase inhibitors) bac...

Eligibility Criteria

Inclusion

  • on TDF/FTC/EFV for more than 3 months
  • Blood HIV RNA viral load \<50 copies/mL
  • CD4+ count \>200 cells/mm3
  • eligible to sign the informed consent

Exclusion

  • history of NRTI resistance
  • on medication that potentially interact with study drug
  • denied to participate in the study

Key Trial Info

Start Date :

October 27 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2018

Estimated Enrollment :

246 Patients enrolled

Trial Details

Trial ID

NCT03251690

Start Date

October 27 2016

End Date

April 30 2018

Last Update

May 7 2019

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