Status:
COMPLETED
Fixed Versus Weight-Based Enoxaparin Dosing in Thoracic Surgery Patients
Lead Sponsor:
University of Utah
Collaborating Sponsors:
University of Michigan
Conditions:
Venous Thromboembolism
Deep Venous Thrombosis
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The aim of this research is to better understand how patient-level factors can be used to predict the appropriate enoxaparin dose to maximize venous thromboembolism (VTE) risk reduction and minimize b...
Detailed Description
VTE encompasses deep venous thrombosis and pulmonary embolus and is the proximate cause of death in over 100,000 hospitalized patients per year 4,5. To put this in better context, VTE kills more peopl...
Eligibility Criteria
Inclusion
- receiving Video-Assisted Thoracoscopic Surgery
- able to have Enoxaparin initiated within 8 hours after procedure
Exclusion
- Contraindication to use of enoxaparin
- Intracranial bleeding/stroke
- Hematoma or bleeding disorder
- Heparin-induced thrombocytopenia positive
- Creatinine clearance less than or equal to 30 mL/min
- Serum creatinine greater than 1.6 mg/dL
- Epidural catheter
Key Trial Info
Start Date :
September 15 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 27 2019
Estimated Enrollment :
131 Patients enrolled
Trial Details
Trial ID
NCT03251963
Start Date
September 15 2017
End Date
July 27 2019
Last Update
July 8 2020
Active Locations (1)
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1
University of Utah
Salt Lake City, Utah, United States, 84112