Status:
UNKNOWN
Effects of Photobiomodulation on Endothelial Function in Healthy Subjects
Lead Sponsor:
Rodrigo Della Méa Plentz
Collaborating Sponsors:
Federal University of Health Science of Porto Alegre
Conditions:
Healthy Behavior
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The endothelial cell layer is responsible for the control of vascular homeostasis, a process mediated by vasoconstricting and vasodilatory substances. The principal endothelium-dependent vascular dila...
Detailed Description
Detailed Description: The endothelial cell layer is responsible for the control of vascular homeostasis, a process mediated by vasoconstricting and vasodilatory substances. The principal endothelium-d...
Eligibility Criteria
Inclusion
- Age between 18-40 years
- Body mass index (BMI: kg / m2) lower than 30
- Absence of symptoms of musculoskeletal disorders
- No use of medications
- Non-smokers and / or alcoholics
- Absence of previous diagnosis of diseases Rheumatological, cardiovascular, renal, metabolic, neurological, oncological, immunological, hematological, psychiatric or cognitive.
Exclusion
- On the days of evaluation and intervention:
- Individuals who performed high intensity physical activity in the previous 72 hours
- Individuals who had an inflammatory response (\> 3 mg / dL, fibrinogen \<200 or\> 400mg / dL) or leukocytosis (\> 11,000 x103 / Mm3)
- Individuals who have consumed caffeine, juices or citrus fruits, high-fat foods and alcohol in the 12 hours prior to the test
- Individuals who are not fasting for 12 hours
- Individuals who have used anti-inflammatory, antipyretic or analgesic drugs
- Individuals who having an arterial diameter \<0.25 mm or\> 5.0 mm
- Individuals with present endothelial dysfunction evaluated by the FMD technique (dilation \<8%).
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2020
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03252184
Start Date
September 1 2017
End Date
December 30 2020
Last Update
March 24 2020
Active Locations (1)
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1
Federal University of Health Science of Porto Alegre (UFCSPA)
Porto Alegre, Rio Grande do Sul, Brazil, 90050170