Status:
COMPLETED
Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation
Lead Sponsor:
Ain Shams University
Conditions:
Gingival Hyperpigmentaion
Eligibility:
All Genders
18-40 years
Phase:
PHASE4
Brief Summary
Vitamin C affect the melanocytes function not the number while diode laser cause melanocytes destruction. Although diode laser and vitamin C have proved their effectiveness in depigmentation in previo...
Detailed Description
Cosmetic dentistry is usually centered on aesthetic restorative procedures but it may also involve the appearance of the gingiva, especially when it is located in the anterior labial region. Oral pigm...
Eligibility Criteria
Inclusion
- Male and female patients with age ranging from 18 years old to 40 years old.
- Bilaterally symmetric gingival hyperpigmentation on the maxillary and mandibular labial keratinized gingiva between canines.
- Patients free from any systemic diseases as evidenced by the health questionnaire, using modified Cornell medical index (Pendleton et al., 2004).
- Patients with thick gingival biotype ≥ 3 mm.
Exclusion
- Presence of local condition that may cause gingival hyperpigmentation (traumatized epithelium caused by defective fixed prosthesis or restoration).
- Smokers.
- Pregnant or lactating females.
- Patients with poor oral hygiene, incompliance to treatment and persistence gingival inflammation after phase I periodontal therapy.
- Clinically diagnosed periodontitis (attachment and bone loss, presence of periodontal pockets, gingival recession and tooth mobility).
- Previous treatment to pigmentation.
- Patients taking supplementary vitamin C for any reason.
- Known sensitivity to ascorbic acid or any of its derivatives.
- Patients taking any drug that may cause gingival pigmentation.
Key Trial Info
Start Date :
October 7 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 10 2016
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03252418
Start Date
October 7 2015
End Date
September 10 2016
Last Update
August 22 2017
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