Status:
TERMINATED
Genetic Variants and Chemotherapy-induced Abnormal Thermal Sensation
Lead Sponsor:
National Cheng-Kung University Hospital
Conditions:
Chemotherapy-induced Abnormal Thermal Sensation
Eligibility:
All Genders
20+ years
Brief Summary
This is a prospective, single arm, single center study evaluating the use of a 4-gene panel to predict the occurrence of chemotherapy-induced abnormal thermal threshold in endometrial and ovarian canc...
Eligibility Criteria
Inclusion
- Age ≥ 20 years old
- Pathological stage I\~IV for ovarian cancer, stage II\~IV for endometrial cancer, or stage III for colorectal cancer.
- Scheduled to receive adjuvant Paclitaxel/Carboplatin for ovarian or endometrial cancer, or mFOLFOX6 for colorectal cancer.
- Patient willing to provide blood sample for research purposes.
- Ability of the patient to provide informed consent.
Exclusion
- Prior treatment with neurotoxic chemotherapy, such as oxaliplatin, cisplatin, carboplatin, taxanes or vinca alkaloids.
- Receiving chemotherapy within 6 months.
- A family history of a genetic or familial neuropathy
- Poor compliance
Key Trial Info
Start Date :
July 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 11 2020
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT03252834
Start Date
July 1 2017
End Date
December 11 2020
Last Update
July 14 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Cheng Kung University Hospital
Tainan, Taiwan, 704