Status:

UNKNOWN

Clinical Study of Microchimerism and cfDNA as Biomarkers for Acute Rejection After Organ Transplantation

Lead Sponsor:

Fuzhou General Hospital

Collaborating Sponsors:

309th Hospital of Chinese People's Liberation Army

Tianjin First Central Hospital

Conditions:

Organ Transplant Rejection

Eligibility:

All Genders

18-70 years

Brief Summary

Organ transplantation has become an effective therapy for patients with end-stage organ failure at present. Rejection is still the most common cause of early dysfunction after organ transplantation. A...

Detailed Description

Organ transplantation has become an effective therapy for patients with end-stage organ failure at present. Since the launch of pilot voluntary organ donation after death of citizens in 2010, the volu...

Eligibility Criteria

Inclusion

  • Single-organ transplant recipients aged above 18 years old Recipients of re-do organ transplants
  • Recipients with no systemic acute or chronic infections, infectious diseases;
  • Recipients with no severe systemic diseases and/or spiritual system diseases
  • Recipients or families signed the consent form.

Exclusion

  • Organ transplant recipients whose donor is child (under the age of 18 years old)
  • Patients wait-listed for multiple organ transplantation
  • Unable or unwilling to follow up regularly

Key Trial Info

Start Date :

March 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

950 Patients enrolled

Trial Details

Trial ID

NCT03255265

Start Date

March 1 2017

End Date

December 31 2021

Last Update

August 21 2017

Active Locations (1)

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Fuzhou General Hospital, Xiamen Univ Fuzhou, Fujian China

Fuzhou, Fujian, China, 350025