Status:
UNKNOWN
Vertical Exposure to Zika Virus and Its Consequences for Child Neurodevelopment (ZIKVIRUSIFF)
Lead Sponsor:
Oswaldo Cruz Foundation
Collaborating Sponsors:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Rio de Janeiro State Research Supporting Foundation (FAPERJ)
Conditions:
ZIKA VIRUS INFECTION
Child Development
Eligibility:
All Genders
2-3 years
Brief Summary
The recent increase in the number of cases of congenital microcephaly observed in Brazil is a reason of great concern. This increase occurred a few months after Zika virus (ZIKV) was introduced in the...
Detailed Description
The mais goal of the study is to assess the natural history of vertical ZIKV transmission from pregnancy to the end of third year of life and the existence of risk factors associated with the incidenc...
Eligibility Criteria
Inclusion
- The study population will be composed of pregnant women who present symptoms compatible with ZIKAV infection, with skin rash, arthralgia-associated fever, myalgia, non-purulent conjunctivitis, or headache and asymptomatic pregnant women identified at the same time of possibility of exposure. We will include patients with RT- PCR positive.
- All pregnant women who are in the prenatal follow up at IFF and CSGSF, irrespective of the gestational age, are elegible as a not exposed in the beginning.
- Children born during the outbreak by mothers with confirmed infection, suspected infection and normal pregnancy
Exclusion
- Pregnant women with chromosomal abnormalities detected during fetal life or birth will be excluded.
- \-
Key Trial Info
Start Date :
January 2 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2019
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT03255369
Start Date
January 2 2016
End Date
December 30 2019
Last Update
May 3 2018
Active Locations (1)
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1
Instituto Fernandes Figueira/Fiocruz
Rio de Janeiro, Rio de Janeiro, Brazil, 22250020