Status:
RECRUITING
Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy For Locally Advanced Breast Cancer
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Conditions:
Breast Cancer
Locally Advanced Breast Cancer
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
This study is being done to help the investigators determine how accurate the sentinel lymph node biopsy (SLNB) procedure is in identifying residual cancer cells after neoadjuvant chemotherapy in pati...
Eligibility Criteria
Inclusion
- Female patients over 18 years of age with biopsy-proven breast cancer
- Patients presenting with locally advanced disease in the breast (cT4) and/or in the nodes (cN2/N3) as assessed by clinical exam and imaging
- Patients presenting to surgery clinic after receipt of NAC at outside hospital with documentation of cT4 or cN2/3 disease on initial outside physical exam and imaging studies
- Patients receiving NAC and having a nodal complete clinical response as assessed by physical exam
Exclusion
- Patients with a prior history of ipsilateral breast cancer
- Pregnant patients
- Patients with persistent palpable axillary nodes after NAC, as assessed by physical exam
- Patients not consenting to ALND
Key Trial Info
Start Date :
August 17 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 30 2026
Estimated Enrollment :
170 Patients enrolled
Trial Details
Trial ID
NCT03255577
Start Date
August 17 2017
End Date
August 30 2026
Last Update
July 23 2025
Active Locations (8)
Enter a location and click search to find clinical trials sorted by distance.
1
BAPTIST ALLIANCE - MCI (Data Collection Only)
Miami, Florida, United States, 33143
2
Memorial Sloan Kettering at Basking Ridge (Consent and Follow Up)
Basking Ridge, New Jersey, United States, 07920
3
Memorial Sloan Kettering Monmouth
Middletown, New Jersey, United States, 07748
4
Memorial Sloan Kettering Bergen (Consent only and Follow Up)
Montvale, New Jersey, United States, 07645