Status:

COMPLETED

Low Back Pain: Unveiling the Contribution of Motor Control Adaption Using Biomechanical Modeling and Neuroimaging

Lead Sponsor:

Balgrist University Hospital

Collaborating Sponsors:

Psychiatric University Hospital, Zurich

Bern University of Applied Sciences

Conditions:

Low Back Pain

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

This project aims to reveal the potential sensorimotor reorganization of sensory input in low back pain patients and its association with different motor control strategies in LBP.

Detailed Description

Background: Low back pain (LBP) is a major health issue. Treatment of chronic LBP is still a major challenge due to a lack of pathophysiological understanding. Thus, understanding LBP pathophysiology ...

Eligibility Criteria

Inclusion

  • Inclusion criteria healthy subjects:
  • Aged between 18 and 60
  • Written informed consent after being informed
  • Inclusion criteria low back pain patients:
  • Aged between 18 and 60
  • Low back pain for more than 1 week
  • Exclusion criteria healthy subjects:
  • Consumption of alcohol, drugs, analgesics within the last 24 h
  • Pregnancy
  • acute and/or low recurrent back pain within the last 3 months
  • Prior spine surgery
  • Other chronic pain condition
  • history of psychiatric or neurological disorders
  • MR-contraindications
  • Body mass index (BMI) \> 30 kg/m2
  • Exclusion criteria low back pain patients:
  • Consumption of alcohol, drugs, analgesics within the last 24 h
  • Pregnancy
  • Specific causes for the back pain (ruled out by the clinician)
  • Prior spine surgery
  • History of psychiatric or neurological disorders
  • MR-contraindications
  • Body mass index (BMI) \> 30 kg/m2

Exclusion

    Key Trial Info

    Start Date :

    April 1 2019

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    January 17 2023

    Estimated Enrollment :

    80 Patients enrolled

    Trial Details

    Trial ID

    NCT03255616

    Start Date

    April 1 2019

    End Date

    January 17 2023

    Last Update

    January 18 2023

    Active Locations (1)

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    1

    Balgrist University Hospital

    Zurich, Switzerland, 8008