Status:

COMPLETED

The Effect of Peri-percutaneous Coronary Intervention Oxygenation on Myocardial Protection & Cardiovascular Fitness

Lead Sponsor:

University of Malaya

Conditions:

Myocardial Ischemia

Cardiovascular Morbidity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Elective percutaneous coronary intervention (PCI) is often associated with myocardial necrosis evidenced by peri-procedural troponin release. This is a surrogate for subsequent cardiovascular events. ...

Detailed Description

OBJECTIVE: This study is to assess the utility of oxygen to reduce ischaemia in patients with significant stable coronary artery disease scheduled for elective PCI. The secondary objective is to evalu...

Eligibility Criteria

Inclusion

  • Patients aged \>18 years
  • Haemodynamically important coronary artery disease (\>70% luminal stenosis angiographically in ≥1 major epicardial coronary artery

Exclusion

  • Significant chronic airways disease with type-2 respiratory failure precluding safe use of oxygen
  • Coronary stenoses where evidence of plaque instability is evident e.g. rest pain, visual evidence of thrombus, elevation of Troponin T at baseline

Key Trial Info

Start Date :

July 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2016

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03256175

Start Date

July 1 2015

End Date

June 30 2016

Last Update

October 25 2017

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