Status:
ACTIVE_NOT_RECRUITING
Effect of Antigens or Therapeutic Agents on in Vitro Human Intestinal Organoids
Lead Sponsor:
University of Erlangen-Nürnberg Medical School
Conditions:
Intestine Disease
Eligibility:
All Genders
18+ years
Brief Summary
The study evaluates the effect of nutrient antigens or therapeutic agents on human small intestinal organoids.
Detailed Description
Small intestinal biopsies will be taken to establish human intestinal organoids in vitro. The organoids will be propagated and various antigens will be checked for their effects on proliferation, prod...
Eligibility Criteria
Inclusion
- patients with gastrointestinal disorders and therapeutical indication of gastroduodenoscopy or coloscopy
- healthy controls for preventive medical check-up
Exclusion
- pregnant women
Key Trial Info
Start Date :
April 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
375 Patients enrolled
Trial Details
Trial ID
NCT03256266
Start Date
April 1 2017
End Date
July 1 2025
Last Update
July 5 2024
Active Locations (1)
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1
Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg
Erlangen, Germany, 91052