Status:
COMPLETED
Intraoperative PEEP Setting During Laparoscopic Gynecologic Surgery
Lead Sponsor:
Mahidol University
Conditions:
Positive-Pressure Respiration/Methods
Esophagus/Physiopathology
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
The creation of pneumoperitoneum during laparoscopic surgery can have significant effects on the respiratory system including decreased respiratory system compliance, decreased vital capacity and func...
Detailed Description
As minimally invasive procedure with numerous advantages compared with open surgery, laparoscopic surgery has been substantially performed worldwide. The creation of pneumoperitoneum during laparoscop...
Eligibility Criteria
Inclusion
- Patients with age of equal or more than 18 years old undergoing laparoscopic gynecologic surgery with anticipated surgical duration of more than 2 hours
Exclusion
- Patients with ASA physical status of equal or more than 3
- Patients with significant cardiovascular or respiratory diseases
- Patients with significant pathological lesion in pharynx and esophagus that preclude placement of esophageal balloon catheter
- Patients with contraindications for PEEP titration such as increased intracranial pressure or unstable hemodynamic
- Patients with arrhythmias
- Patients who refuse to provide written informed consent
- Patients undergoing surgery with duration of less than 2 hours
Key Trial Info
Start Date :
March 30 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 28 2018
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT03256396
Start Date
March 30 2018
End Date
December 28 2018
Last Update
August 22 2019
Active Locations (1)
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1
Siriraj Hospital
Bangkoknoi, Bangkok, Thailand, 10700