Status:

COMPLETED

Detecting Transitional Cell Carcinoma From Haematuria

Lead Sponsor:

Hull University Teaching Hospitals NHS Trust

Collaborating Sponsors:

C-Term Diagnostics Ltd

Hull York Medical School

Conditions:

Transitional Cell Carcinoma

Eligibility:

All Genders

18+ years

Brief Summary

To validate ELISAs for the detection of urinary tissue factor (TF) in patients suspected of having bladder cancer.

Detailed Description

The effective diagnosis of transitional cell carcinoma (TCC), the most common form of bladder cancer, is often quite challenging, due to a lack of disease-specific symptoms. Detecting TCC early is cru...

Eligibility Criteria

Inclusion

  • Capable of giving written informed consent
  • Age ≥18 years
  • Referral to haematuria clinic (gross or microscopic haematuria)

Exclusion

  • Inability to provide written informed consent
  • Previous radiotherapy to the bladder (e.g. prostate cancer)
  • Active urinary tract infection (Patients may be re-approached at later opportunity when urinary infection is cleared and haematuria persists)
  • Current or planned treatment with neoadjuvant chemotherapy or radiotherapy
  • Other known malignant condition, either active or in complete remission ≤5 years
  • HIV, hepatitis C, or any other known communicable disease

Key Trial Info

Start Date :

October 18 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 16 2019

Estimated Enrollment :

750 Patients enrolled

Trial Details

Trial ID

NCT03256877

Start Date

October 18 2016

End Date

May 16 2019

Last Update

July 29 2019

Active Locations (1)

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1

Castle Hill Hospital

Hull, United Kingdom, HU16 5JQ