Status:

COMPLETED

Breakfast Consumption and Its Effects on Glycemic, Insulinemic and Non-Esterified Fatty Acids Responses

Lead Sponsor:

JeyaKumar Henry

Collaborating Sponsors:

General Mills

Conditions:

Glycemic Response

Eligibility:

MALE

40-65 years

Phase:

NA

Brief Summary

The aim of this study is to determine whether eating breakfast or having no breakfast has subsequent beneficial health effects, specifically in relation to glycemic response throughout the day and pos...

Detailed Description

This will be a randomised, crossover study with two treatments in total. 1.) Subjects given with breakfast, 2.) Subjects not given breakfast. Each of the two test visits will last for approximately 9 ...

Eligibility Criteria

Inclusion

  • Chinese males
  • BMI above 23.0 kg/m2
  • Age between 40-65 years
  • Normal blood pressure (\<140/90 mmHg)
  • Fasting blood glucose of ≥5.6 mmol/L
  • Self-reported regular breakfast consumers

Exclusion

  • Have known glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • major chronic disease such as heart disease, cancer or diabetes mellitus
  • taking insulin or drugs known to affect glucose metabolism
  • Intentionally restrict food intake
  • major medical or surgical event requiring hospitalization within the preceding 3 months
  • Have taken antibiotics for 3 months before the study period
  • Smoking
  • Overnight shift workers
  • Any known food allergy (eg. anaphylaxis to peanuts)
  • Having active Tuberculosis (TB) or currently receiving treatment for TB
  • Any known Chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV)
  • Being a member of the research team or their immediate family members. Immediate family member is defined as a spouse, parent, child, or sibling, whether biological or legally adopted.
  • Enrolled in a concurrent research study judged not to be scientifically or medically compatible with the study of the CNRC.

Key Trial Info

Start Date :

July 25 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 28 2019

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT03257059

Start Date

July 25 2017

End Date

March 28 2019

Last Update

May 13 2019

Active Locations (1)

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Clinical Nutrition Research Centre

Singapore, Singapore, 117599