Status:
UNKNOWN
Hypothyroidism in Patients With Type 1 Diabetes
Lead Sponsor:
Assiut University
Conditions:
Hypothyroidism
Eligibility:
All Genders
8-15 years
Brief Summary
Therefore, for early detection of hypothyroidism in children with type 1 diabetes, it is suggested to measure anti-thyroid antibodies and thyroid stimulating hormone at disease onset and in yearly int...
Detailed Description
Type 1 diabetes is an organ-specific autoimmune disease characterized by the selective destruction of pancreatic β-cells. The histopathology of type 1 diabetes is defined by a decreased β-cell mass in...
Eligibility Criteria
Inclusion
- \- Children with type 1 diabetes aging between 8 - 15 y .
Exclusion
- Cases with hyperthyroidism .
- Areas known to have endemic goitre due to nutritional iodine deficiency .
- History of maternal hypothyroidism and / or congenital hypothyroidism .
- Children known to be normoglycaemic with already presented thyroid dysfunction .
- Children with multiple endocrinopathies .
- Children under treatment with drugs inducing hypothyroidism like amiodarone , lithium .
- Children under treatment with drugs affecting insulin secretion like steroids , growth hormone therapy .
Key Trial Info
Start Date :
November 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2019
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03257566
Start Date
November 1 2017
End Date
September 1 2019
Last Update
August 22 2017
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