Status:
COMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9
Lead Sponsor:
Assiut University
Conditions:
Preeclampsia
Eligibility:
FEMALE
18-40 years
Brief Summary
Preeclampsia is a pregnancy related disease characterized by the new onset of hypertension and proteinuria after 20 weeks of gestation in previously normotensive women. PE is one of the most challengi...
Detailed Description
The etiology and pathophysiology of preeclampsia are still unclear but the impaired invasive ability of the trophoblast cells of the placenta and vascular endothelial cell damage are the main two fact...
Eligibility Criteria
Inclusion
- Pregnant women who come for termination of pregnancy by vaginal delivery or CS between 28-34 weaks gestational age in Assiut university maternity hospital in the age range of 18-40 years.
Exclusion
- 1\) Diabetes mellitus 2) Chronic hypertension 3) Nephropathy 4) Acute or chronic infectious diseases or other chronic illness 5) Twins pregnancy 6) Anti phospholipid antibody syndrome 7) PE complicated with eclampsia, DIC or HELP syndrome
Key Trial Info
Start Date :
January 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2020
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03258125
Start Date
January 1 2019
End Date
June 1 2020
Last Update
June 24 2020
Active Locations (1)
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1
Faculty of Medicine
Asyut, Egypt